Subclinical Hypothyroidism in Advanced Chronic Kidney Disease Patients: Prevalence and Associated Factors
Table 1
Clinical characteristics of the study population.
All, 299 (100%)
SH present, 54 (18.1%)
SH absent, 245 (81.9%)
Age (years)
71 ± 13
76 ± 11
69 ± 13
<0.001
Gender (male)
184 (61.5%)
33 (61.1%)
151 (61.6%)
0.9
Hypertension
241 (80.6%)
49 (90.7%)
192 (78.4%)
0.03
Diabetes mellitus
117 (39.1%)
29 (38.9%)
96 (39.2%)
0.9
Dyslipidemia
219 (73.2%)
42 (77.8%)
177 (77.2%)
0.06
CV disease history
137 (45.8%)
29 (53.7%)
108 (44.1%)
0.05
Hemoglobin (g/dL)
12.2 ± 1.4
12.3 ± 1.2
12.1 ± 1.4
0.3
Parathyroid hormone (pg/mL)
174 ± 96
185 ± 115
172 ± 91
0.08
TSH (mU/L)
3.1 ± 1.6
6 ± 0.8
2.5 ± 1
<0.001
fT4 (ng/dL)
1 ± 0.6
0.9 ± 0.1
0.9 ± 0.6
0.8
CKD EPI (ml/min/1.73 m2)
22 ± 9
19 ± 9
22 ± 9
0.02
Proteinuria > 1 gram per day
90 (30.1%)
25 (46.3%)
65 (26.5%)
0.004
Patients were divided according to the presence of subclinical hypothyroidism. CV: cardiovascular; TSH: thyroid-stimulating hormone; fT4: free thyroxine.
