Research Article
Clinicopathological Profile of Thyroid Carcinoma in Young Patients: An Indonesian Single-Center Study
Table 1
Baseline characteristics of study subjects.
| | Characteristic | Number of patients (n = 29) |
| | Age, years (mean ± SD, range) | 14 ± 3.7, 5–20 | | Sex (n, %) | | Boys | 3 (10.3) | | Girls | 26 (89.7) | | Thyroid parameters (median, range) | | TSH (μIU/mL) | 1.37, 0.0025–83.50 | | fT4 (ng/dL) | 1.08, 0.49–4.25 | | Pathological characteristics | | Tumor size, cm (mean ± SD), (range) | 2.5 ± 2.6, 0.3–15 | | Tumor type | | Papillary thyroid carcinoma (PTC) | 28 (96.5) | | Hurthle cell carcinoma | 1 (3.4) | | PTC variant (n, %) | | Classic | 6 (20.7) | | Tall cell | 8 (27.6) | | Follicular | 9 (31) | | Microcarcinoma | 5 (17.2) | | Multifocality | 15 (51.7) | | Background thyroid inflammation | 0 (0) | | Lymphovascular invasion (LVI) | 7 (24.1) | | Soft tissue invasion | 3 (10.3) | | Capsular invasion | 8 (27.6) | | Surgical margin | | Positive margin | 5 (17.2) | | Negative margin | 22 (75.9) | | Unknown | 2 (6.9) | | Distant metastasis | 5 (17.2) | | Intervention (n, %) | | Surgical intervention | | Hemithyroidectomy | 9 (31.0) | | Subtotal thyroidectomy | 5 (17.2) | | Total thyroidectomy | 15 (51.7) | | Radioactive iodine (RAI) therapy | 11 (37.9) | | MACIS score (mean, range) | 4.8, 3.25–8.75 | | Recurrence | 9 (31) | | Mortality | 0 (0) |
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SD: standard deviation; n: number; MACIS: distant metastasis, patient age, completeness of resection, local invasion, and tumor size; μIU: microinternational unit; mL: milliliter; ng: nanogram; dL: deciliter.
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