Journal of Thyroid Research

Thyroid and Pregnancy


Publishing date
15 Aug 2011
Status
Published
Submission deadline
15 Feb 2011

Lead Editor

1Peninsula Medical School, Royal Devon & Exeter Hospital, Exeter, UK

2Division of Endocrinology, V. Fazzi Hospital, Lecce, Italy

3Department of Paediatrics, Hospital for Sick Children, Toronto, ON, Canada


Thyroid and Pregnancy

Description

In the last two decades, there have been major advances in our understanding of thyroid physiology during pregnancy and the role of thyroid hormones in fetal development. Increasing evidence during the period has highlighted that even mild maternal thyroid dysfunction can have adverse effects on fetal neuropsychological development and other pregnancy outcomes. The importance of trimester-specific reference ranges for thyroid function tests in pregnancy has emerged. Randomised controlled trials are beginning to provide evidence base for the management of various thyroid disorders in pregnancy.

However, there remain many unanswered questions in relation to thyroid and pregnancy. For example, how does maternal thyroid hormone transport to the fetus and influence fetal brain development at the molecular level? There is lack of consensus on several clinical management issues. For example, should all pregnant women be screened for thyroid dysfunction, what are the cut-off levels for maternal subclinical hypothyroidism and maternal hypothyroxinemia in pregnancy, and when to start treatment for these conditions? Also, despite all national and international programs to optimise dietary iodine intake in the populations, iodine deficiency during pregnancy continues to be a major preventable cause of mental retardation in many countries. Furthermore, the recent studies have raised concerns about potential adverse effects of environmental thyroid hormone disruptors on pregnancy outcomes.

The main focus of this special issue will be pregnancy-related thyroid disorders. We invite authors to submit original research (clinical or basic science) as well as review articles that will enhance our understanding of thyroid physiology and pathology in relation to pregnancy. We are also interested in articles exploring adverse effects and management of thyroid dysfunction in pregnancy. Potential topics include, but are not limited to:

  • Physiological, environmental, and genetic factors affecting thyroid function in pregnancy
  • Thyroid and fetal brain development
  • Iodine deficiency and pregnancy
  • Congenital hypothyroidism
  • Transient hypothyroxinemia of prematurity
  • Thyroid in relation to infertility and its treatment
  • Thyroid autoimmunity and pregnancy
  • Thyroid hormone insufficiency and pregnancy
  • Hyperthyroidism and pregnancy
  • Postpartum thyroid dysfunction
  • Goitre, thyroid lump, and thyroid cancer in pregnancy
  • Thyroid surgery in pregnancy
  • Environmental thyroid hormone disruptors and pregnancy

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/jtr/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2011
  • - Article ID 680328
  • - Editorial

Thyroid and Pregnancy

Bijay Vaidya | Roberto Negro | ... | Joanne Rovet
  • Special Issue
  • - Volume 2011
  • - Article ID 426427
  • - Research Article

Maternal Thyroid Function during the Second Half of Pregnancy and Child Neurodevelopment at 6, 12, 24, and 60 Months of Age

Jonathan Chevrier | Kim G. Harley | ... | Brenda Eskenazi
  • Special Issue
  • - Volume 2011
  • - Article ID 235130
  • - Research Article

Suspected Spontaneous Reports of Birth Defects in the UK Associated with the Use of Carbimazole and Propylthiouracil in Pregnancy

Pamela Bowman | Bijay Vaidya
  • Special Issue
  • - Volume 2011
  • - Article ID 342189
  • - Review Article

Do Thyroid Disrupting Chemicals Influence Foetal Development during Pregnancy?

Marie-Louise Hartoft-Nielsen | Malene Boas | ... | Ulla Feldt-Rasmussen
  • Special Issue
  • - Volume 2011
  • - Article ID 843591
  • - Review Article

Levothyroxine Treatment in Pregnancy: Indications, Efficacy, and Therapeutic Regimen

Joanna Klubo-Gwiezdzinska | Kenneth D. Burman | ... | Leonard Wartofsky
  • Special Issue
  • - Volume 2011
  • - Article ID 691719
  • - Review Article

Prognosis of Thyroid Cancer Related to Pregnancy: A Systematic Review

Gustavo Vasconcelos Alves | Ana Paula Santin | Tania Weber Furlanetto
  • Special Issue
  • - Volume 2011
  • - Article ID 429097
  • - Clinical Study

Prevalence and Impact of Thyroid Disorders on Maternal Outcome in Asian-Indian Pregnant Women

Vimal Nambiar | Varsha S. Jagtap | ... | Nalini S. Shah
  • Special Issue
  • - Volume 2011
  • - Article ID 142413
  • - Research Article

Transient Non-Autoimmune Hyperthyroidism of Early Pregnancy

Alexander M. Goldman | Jorge H. Mestman
  • Special Issue
  • - Volume 2011
  • - Article ID 745135
  • - Review Article

Thyroid Peroxidase Antibody and Screening for Postpartum Thyroid Dysfunction

Mohamed A. Adlan | Lakdasa D. Premawardhana
  • Special Issue
  • - Volume 2011
  • - Article ID 463029
  • - Review Article

Doubts and Concerns about Isolated Maternal Hypothyroxinemia

Mariacarla Moleti | Francesco Trimarchi | Francesco Vermiglio
Journal of Thyroid Research
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