Journal of Transplantation / 2009 / Article / Tab 3

Research Article

Persistence of Hepatitis C RNA in Liver Allografts Is Associated with Histologic Progression Independent of Serologic Viral Clearance

Table 3

Antiviral treatment duration and outcomes collated by patient group, HCV genotype, timing of ISH assayed biopsy and virologic response.

Group, genotype and case numberISH StatusTreatment duration at ISH assay (months)Total treatment duration (months)Viral load responseHCV undetectable by 12 weeksHCV undetectable by 24 weeksOutcome

Group 1, genotype 2 or 3

1 + 1212EVRNoYesSVR
2 + 1218EVRNAYesSVR
3 + 2126RVRYesSVR
4 + 1437EVRYesOn therapy

Group 1, genotype 1 or unknown*

5 + 418EVRNoYesRelapse
6 + 519EVRYesSVR
7* + 918EVRYesSVR
8 + 1421No EVRNoYesSVR
9 + 2146EVRNAYesSVR
10 + 1322EVRYesSVR

Group 2, genotype 2 or 3

11 711RVRYesSVR
12 99No EVRNoYesRelapse

Group 2, genotype 1 or unknown*

13 1011EVRNAYesSVR
14 812EVRNAYesRelapse
15 611RVRYesSVR
16* 812EVRYesSVR
17 1013EVRYesRelapse
18 1414EVRNAYesSVR
19 1112EVRNoYesRelapse
20 2033No EVRNoNoSVR
21 312EVRYesSVR
22 1414NANAYesSVR
23 712EVRNoYesRelapse
24 1317EVRNoYesSVR
25 1213EVRYesRelapse

NA: Not available; EVR: Early virologic response; RVR: Rapid virologic response; SVR: Sustained viral response.
*The patients that did not have a known genotype.