How to Recondition Ex Vivo Initially Rejected Donor Lungs for Clinical Transplantation: Clinical Experience from Lund University Hospital
Flowchart showing the first part of the ex vivo reconditioning of donor lungs initially rejected donor lungs for clinical transplantation. During the first part of the process, the lungs are not ventilated and the perfusate blood is oxygenated. The temperature of the perfusate is gradually increased with a gradient ≤10°C to 32°C. The initial perfusion flow was 50–100 mL/min. The flow was slowly increased, and the pulmonary pressure was kept at ≤20 mmHg. The left atrium pressure was maintained at 0 mmHg to prevent the development of edema.
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