Review Article
Pancreas Procurement and Preservation for Islet Transplantation: Personal Considerations
Table 1
Composition and other characteristics of each preserving solution.
| | ET-K | MK | UW | HNC | M-HTK |
| | Na (mmol/L) | 100 | 100 | 29 | 100 | 15 | | K (mmol/L) | 43.5 | 43.5 | 125 | 15 | 10 | | Mg (mmol/L) | — | — | 5 | 13 | 4 | | Ca (mmol/L) | — | — | — | 0.25 | 0.015 | | Cl (mmol/L) | — | — | — | 41 | 50 | | Gluconate (mmol/L) | 100 | 100 | — | — | — | | Phosphate (mmol/L) | 25 | 25 | 25 | — | — | | Sulfate (mmol/L) | — | — | 5 | — | — | | Lactobionate (mmol/L) | — | — | 100 | 80 | — | | Raffinose (mmol/L) | — | — | 30 | — | — | | Trehalose (mmol/L) | 120 | 120 | — | — | — | | Adenosine (mmol/L) | — | — | 5 | — | — | | Alloprinol (mmol/L) | — | — | 1 | — | — | | Glutathione (mmol/L) | — | — | 3 | 3 | — | | HES (g/L) | 30 | 30 | 50 | 30 | — | | Ulinastatin (×103 U/L) | — | 100 | — | — | 100 | | Nafamostat mesilate (mg/L) | — | — | — | 20 | — | | Histidine (mmol/L) | — | — | — | 30 | 198 | | Mannitol (mmol/L) | — | — | — | 60 | 30 | | α-ketoglutarate (mmol/L) | — | — | — | — | 1 | | Tryptophan (mmol/L) | — | — | — | — | 2 | | Glutamic acid (mmol/L) | — | — | — | 20 | — | | Osmolality (mOsm) | 366 | 366 | 320 | 355 | 310 |
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HES: hydroxyethyl starch; ROS: reactive oxygen species; ET-K: ET-Kyoto solution; MK: modified ET-Kyoto solution; UW: University of Wisconsin solution; HNC: Celsior solution with HES and nafamostat mesilate; M-HTK: modified histidine-tryptophan-ketoglutarate solution.
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