Figure 4: Life-supporting kidney Tx was carried out from a nonirradiated donor into a recipient immunosuppressed for 42 days with tacrolimus. Efforts were made to maintain the 12 h blood trough level between 10–15 ng/mL. Serum creatinine levels remained between 132.6–176.8 μmol/L (1.5–2.0 mg/dL) for almost 5 months after discontinuing tacrolimus. The pig was euthanized electively 188 days after kidney Tx.