Xenotransplantation of Human Neural Progenitor Cells to the Subretinal Space of Nonimmunosuppressed Pigs

Figure 2

Xenografted human NPCs express GFAP in the porcine subretinal space. Donor cell identified with anti-human nuclear antibody exhibits cytoplasmic labeling for the astroglial marker glial fibrillary acidic protein (GFAP, red), which is also expressed by activated glial cells in the underlying host neural retina. Survival = 10 days.