Journal of Transplantation

Clinical Study

Estimation of Abbreviated Cyclosporine A Area under the Concentration-Time Curve in Allogenic Stem Cell Transplantation after Oral Administration

Table 2

Pharmacokinetic parameters (PK) in allogenic hematopoitic stem cell transplantation.
PK parameters (LSS development group)Values (Mean ± SD)
A U C 0 - 1 2 h (μg·h·mL−1) 4 . 3 4 0 ± 1 . 1 9 5
Through concentration C0 (μg·mL−1) 0 . 4 7 0 ± 0 . 1 7 8
Cmax (μg·mL−1) 0 . 8 3 4 ± 0 . 2 7 9
Tmax (h) 1 . 9 0 8 ± 0 . 9 5 4
Dose (mg) 1 1 3 . 0 ± 4 0 . 8 5
A U C 0 - 1 2 h , area under the concentration-time curve from 0–12 h; Cmax, peak concentration, Tmax, time to reach Cmax; SD, standard deviation.