Creatinine-Based Estimations of Kidney Function Are Unreliable in Obese Kidney Donors

Table 4

Sensitivity and specificity of estimating equations.

	mGFR > 80 mL/min/1.73 m^2
	SENS	SPEC
Normal
CG-CrCl	51%	67%
MDRD eGFR	74%	47%
CKD-EPI eGFR	81%	40%
Class I Obesity
CG-CrCl	47%	69%
MDRD eGFR	81%	46%
CKD-EPI eGFR	86%	23%
Class II/III Obesity
CG-CrCl	45%	92%
MDRD eGFR	100%	17%
CKD-EPI eGFR	100%	17%

Abbreviations: mGFR—measured glomerular filtration rate; SENS—sensitivity; SPEC—specificity; CG-Cockcroft-Gault equation; CrCl—creatinine clearance; MDRD—modification of diet in renal disease; CKD-EPI—chronic kidney disease epidemiology collaboration; eGFR—estimated glomerular filtration rate.