Clinical Study

Efficacy and Safety of Low-Dose Everolimus as Maintenance Immunosuppression in Cardiac Transplant Recipients

Table 1

Characteristics of the patients.

Characteristic1.0 mg of Everolimus ( 𝑁 = 5 1 )1.5 mg of Everolimus ( 𝑁 = 5 6 ) 𝑃 value

Age (years) 6 1 . 9 ± 1 0 . 6 5 9 . 0 ± 1 1 . 5 0.170
Sex (% males)84.382.10.801
Weight (kg) 8 1 . 1 ± 1 2 . 1 7 9 . 6 ± 1 2 . 0 0.533
Height (cm) 1 7 6 ± 7 1 7 4 ± 8 0.165
Primary reason for transplantation
 Dilated cardiomyopathy (%)43.130.40.228
 Coronary heart disease (%)47.164.30.082
 Others (%)9.85.40.474
Diabetes mellitus (%)21.623.20.512
Time since transplantation (months) 7 6 . 8 ± 6 1 . 8 8 0 . 7 ± 6 0 . 0 0.675
Glomerular filtration rate (mL/min/1.73 m2) 3 4 . 4 ± 1 1 . 9 3 5 . 8 ± 1 0 . 3 0.528
Kind of immunosuppression after conversion
 CSA/EVL (%)66.758.90.431
 TAC/EVL (%)33.341.70.431