Table of Contents Author Guidelines Submit a Manuscript
Journal of Transplantation
Volume 2013, Article ID 614610, 8 pages
http://dx.doi.org/10.1155/2013/614610
Review Article

Outcome and Challenges of Kidney Transplant in Patients with Sickle Cell Disease

Renal Unit, Department of Medicine, Enugu State University Teaching Hospital Parklane, Enugu, Nigeria

Received 15 December 2012; Revised 28 February 2013; Accepted 12 March 2013

Academic Editor: Parmjeet Randhawa

Copyright © 2013 U. H. Okafor and E. Aneke. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. O. S. Platt, D. J. Brambilla, W. F. Rosse et al., “Mortality in sickle cell disease. Life expectancy and risk factors for early death,” The New England Journal of Medicine, vol. 330, no. 23, pp. 1639–1644, 1994. View at Publisher · View at Google Scholar · View at Scopus
  2. U. H. Okafor, I. Ekwem, and F. S. Wokoma, “Challenges of kidney care in a resource poor nation: a study of private kidney care centre in Nigeria,” Nigerian Medical Journal, vol. 53, pp. 47–50, 2012. View at Google Scholar
  3. L. W. Status van Eps, Sickle cell disease. Atlas of kidney disease; CD Rom, pp. 1–22, 2004.
  4. V. K. Derebail, P. H. Nachman, N. S. Key, H. Ansede, R. J. Falk, and A. V. Kshirsagar, “High prevalence of sickle cell trait in African Americans with ESRD,” Journal of the American Society of Nephrology, vol. 21, no. 3, pp. 413–417, 2010. View at Publisher · View at Google Scholar · View at Scopus
  5. L. François, H. Nadjib, S. S. Katia et al., “Hemoglobin SC disease complications: a clinical study of 179 cases,” Haematologica, vol. 97, no. 8, pp. 1136–1141, 2012. View at Publisher · View at Google Scholar
  6. R. J. Falk, J. L. Scheinman, G. I. Phillips, E. Orringer, A. Johnson, and J. C. Jennette, “Prevalence and pathologic features of sickle cell nephropathy and response to inhibition of angiotensin-converting enzyme,” The New England Journal of Medicine, vol. 326, no. 14, pp. 910–915, 1992. View at Google Scholar · View at Scopus
  7. J. I. Scheinman, “Tools to detect and modify sickle cell nephropathy,” Kidney International, vol. 69, no. 11, pp. 1927–1930, 2006. View at Publisher · View at Google Scholar · View at Scopus
  8. K. C. Abbott, I. O. Hypolite, and L. Y. Agodoa, “Sickle cell nephropathy at end-stage renal disease in the United States: patient characteristics and survival,” Clinical Nephrology, vol. 58, no. 1, pp. 9–15, 2002. View at Google Scholar · View at Scopus
  9. R. A. Bolarinwa, K. S. Akinlade, M. A. O. Kuti, O. O. Olawale, and N. O. Akinola, “Renal disease in adult Nigerians with sickle cell anaemia: a report of prevalence, clinical features and risk features,” Saudi Journal of Kidney Diseases and Transplantation, vol. 23, no. 1, pp. 171–175, 2012. View at Google Scholar
  10. P. T. T. Pham, P. C. T. Pham, A. H. Wilkinson, and S. Q. Lew, “Renal abnormalities in sickle cell disease,” Kidney International, vol. 57, no. 1, pp. 1–8, 2000. View at Publisher · View at Google Scholar · View at Scopus
  11. J. N. Etteldorf, A. H. Tuttle, and G. W. Clayton, “Renal function studies in pediatrics,” American Journal of Diseases of Children, vol. 83, pp. 185–191, 1952. View at Google Scholar
  12. A. G. Morgan and G. R. Serjeant, “Renal function in patients over 40 with homozygous sickle-cell disease,” British Medical Journal, vol. 282, no. 6271, pp. 1181–1183, 1981. View at Google Scholar · View at Scopus
  13. P. E. De Jong and L. W. Statius van Eps, “Sickle cell nephropathy: new insights into its pathophysiology,” Kidney International, vol. 27, pp. 711–717, 1985. View at Google Scholar
  14. G. A. O. Alleyne, L. W. Statius van Eps, S. K. Addac, G. D. Nicholson, and H. Schouten, “The kidney in sickle cell anemia,” Kidney International, vol. 7, pp. 371–379, 1975. View at Google Scholar
  15. L. W. Statius van Eps and P. E. De Jong, “Sickle cell disease,” in Diseases of the Kidney, R. W. Schrier and C. Gottschalk, Eds., pp. 2201–2219, Little Brown, Boston, Mass, USA, 6th edition, 1997. View at Google Scholar
  16. M. Allon, “Renal abnormalities in sickle cell disease,” Archives of Internal Medicine, vol. 150, no. 3, pp. 501–504, 1990. View at Publisher · View at Google Scholar · View at Scopus
  17. C. A. Vaamonde, “Renal papillary necrosis in sickle cell hemoglobinopathies,” Seminars in Nephrology, vol. 4, no. 1, pp. 48–64, 1984. View at Google Scholar · View at Scopus
  18. G. R. Serjeant, Sickle Cell Disease, Oxford University Press, 1992.
  19. L. Foucan, “A randomized trial of captopril for microalbuminuria in normotensive adults with sickle cell anemia,” American Journal of Medicine, vol. 104, no. 4, pp. 339–342, 1998. View at Publisher · View at Google Scholar · View at Scopus
  20. D. R. Powars, D. D. Elliott-Mills, L. Chan et al., “Chronic renal failure in sickle cell disease: risk factors, clinical course, and mortality,” Annals of Internal Medicine, vol. 115, no. 8, pp. 614–620, 1991. View at Google Scholar · View at Scopus
  21. F. K. Port and A. R. Nissenson, “Outcome of end-stage renal disease in patients with rare causes of renal failure. II. Renal or systemic neoplasms,” Quarterly Journal of Medicine, vol. 73, no. 272, pp. 1161–1165, 1989. View at Google Scholar · View at Scopus
  22. W. H. Barber, M. H. Deierhol, B. A. Julian et al., “Renal transplantation in sickle cell anaemia and sickle cell trait,” Clinical Transplantation, vol. 1, pp. 169–175, 1987. View at Google Scholar
  23. R. Montgomery, G. Zibari, G. S. Hill, and L. E. Ratner, “Renal transplantation in patients with sickle cell nephropathy,” Transplantation, vol. 58, no. 5, pp. 618–620, 1994. View at Google Scholar · View at Scopus
  24. S. N. Chatterjee, “National study on natural history of renal allografts in sickle cell disease or trait,” Nephron, vol. 25, no. 4, pp. 199–201, 1980. View at Google Scholar · View at Scopus
  25. S. N. Chatterjee, “National study in natural history of renal allografts in sickle cell disease or trait: a second report,” Transplantation Proceedings, vol. 19, no. 2, supplement 2, pp. 33–35, 1987. View at Google Scholar · View at Scopus
  26. NIH publications, The Management of Sickle Cell Disease: Renal Abnormalities in Sickle Cell Disease, chapter 19, 4th edition, 2002.
  27. D. J. Miner, D. K. Jorkasky, L. J. Perloff, R. A. Grossman, and J. E. Tomaszewski, “Recurrent sickle cell nephropathy in a transplanted kidney,” American Journal of Kidney Diseases, vol. 10, no. 4, pp. 306–313, 1987. View at Google Scholar · View at Scopus
  28. A. J. Bleyer, L. A. Donaldson, M. McIntosh, and P. L. Adams, “Relationship between underlying renal disease and renal transplantation outcome,” American Journal of Kidney Diseases, vol. 37, no. 6, pp. 1152–1161, 2001. View at Google Scholar · View at Scopus
  29. B. A. Warady and E. K. Sullivan, “Renal transplantation in children with sickle cell disease: a report of the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS),” Pediatric Transplantation, vol. 2, no. 2, pp. 130–133, 1998. View at Google Scholar · View at Scopus
  30. D. Spector, J. B. Zachary, S. Sterioff, and J. Millan, “Painful crises following renal transplantation in sickle cell anemia,” American Journal of Medicine, vol. 64, no. 5, pp. 835–839, 1978. View at Google Scholar · View at Scopus
  31. A. O. Ojo, T. C. Govaerts, R. L. Schmouder et al., “Renal transplantation in end-stage sickle cell nephropathy,” Transplantation, vol. 67, no. 2, pp. 291–295, 1999. View at Publisher · View at Google Scholar · View at Scopus
  32. E. J. O'Rourke, C. M. Laing, A. U. Khan et al., “The case | Allograft dysfunction in a patient with sickle cell disease,” Kidney International, vol. 74, no. 9, pp. 1219–1220, 2008. View at Publisher · View at Google Scholar · View at Scopus
  33. J. I. Scheinman, “Sickle cell disease and the kidney,” Nature Clinical Practice Nephrology, vol. 5, no. 2, pp. 78–88, 2009. View at Publisher · View at Google Scholar · View at Scopus
  34. L. Kim, M. R. Garfinkel, A. Chang, P. V. Kadambi, and S. M. Meehan, “Intragraft vascular occlusive sickle crisis with early renal allograft loss in occult sickle cell trait,” Human Pathology, vol. 42, no. 7, pp. 1027–1033, 2011. View at Publisher · View at Google Scholar · View at Scopus
  35. U. H. Okafor, C. Wachukwu, P. Emem-Chioma, and F. S. Wokoma, “Kidney transplant in a 26 year old Nigerian patient with sickle cell nephropathy,” Case Reports in Nephrology, vol. 2012, Article ID 406406, 4 pages, 2012. View at Publisher · View at Google Scholar
  36. D. C. Brennan, B. J. Lippmann, S. Shenoy, J. A. Lowell, T. K. Howard, and M. W. Flye, “Living unrelated renal transplantation for sickle cell nephropathy,” Transplantation, vol. 59, no. 5, pp. 794–795, 1995. View at Google Scholar · View at Scopus
  37. J. I. Scheinman, “Sickle cell nephropathy,” in Paediatric Neprhology, E. D. Avner, W. E. Harmon, P. Niaudet, and N. Yoshikawa, Eds., pp. 917–930, Lippincott Williams & Wilkins, Philadelphia, Pa, USA, 2004. View at Google Scholar
  38. J. Janik and R. A. Seeler, “Perioperative management of children with sickle hemoglobinopathy,” Journal of Pediatric Surgery, vol. 15, no. 2, pp. 117–120, 1980. View at Google Scholar · View at Scopus
  39. R. Rutledge, R. D. Croom III, and J. W. Davis, “Cholelithiasis in sickle cell anemia: surgical considerations,” Southern Medical Journal, vol. 79, no. 1, pp. 28–30, 1986. View at Google Scholar · View at Scopus
  40. J. R. Gibson, “Anesthesia for sickle cell diseases and other hemoglobinopathies,” Sem Anesthesia, vol. 4, pp. 27–35, 1987. View at Google Scholar
  41. R. Ware, H. C. Filston, W. H. Schultz, and T. R. Kinney, “Elective cholecystectomy in children with sickle hemoglobinopathies. Successful outcome using a preoperative transfusion regimen,” Annals of Surgery, vol. 208, no. 1, pp. 17–22, 1988. View at Google Scholar · View at Scopus
  42. D. W. Esseltine, M. R. N. Baxter, and J. C. Bevan, “Sickle cell states and the anaesthetist,” Canadian Journal of Anaesthesia, vol. 35, no. 4, pp. 385–403, 1988. View at Google Scholar · View at Scopus
  43. G. Bihl, “Kidney transplantation in a patient with sickle cell kidney disease?” Medscape Transplantation, vol. 3, p. 2, 2002. View at Google Scholar
  44. P. K. Donnelly, M. E. Edmunds, and K. O'Reilly, “Renal transplantation in sickle cell disease,” The Lancet, vol. 2, no. 8604, p. 229, 1988. View at Google Scholar · View at Scopus
  45. NIH Publications, The Management of Sickle Cell Disease: Anaesthesia and Surgery, chapter 24, 4th edition, 2002, http://www.nhlbi.nih.gov/.
  46. H. Martin and M. D. Steinberg, “Management of sickle cell disease,” The New England Journal of Medicine, vol. 340, pp. 1021–1030, 1999. View at Google Scholar
  47. L. J. Haywood, “Cardiovascular function and dysfunction in sickle cell anemia,” Journal of the National Medical Association, vol. 101, no. 1, pp. 24–30, 2009. View at Google Scholar · View at Scopus
  48. W. Covitz, M. Espeland, D. Gallagher, W. Hellenbrand, S. Leff, and N. Talner, “The heart in sickle cell anemia: the cooperative study of sickle cell disease (CSSCD),” Chest, vol. 108, no. 5, pp. 1214–1219, 1995. View at Google Scholar · View at Scopus
  49. M. Tsironi and A. Aessopos, “The heart in sickle cell disease,” Acta Cardiologica, vol. 60, no. 6, pp. 589–598, 2005. View at Publisher · View at Google Scholar · View at Scopus
  50. L. Leight, T. H. Snider, G. O. Clifford, and H. K. Hellems, “Hemodynamic studies in sickle cell anemia,” Circulation, vol. 10, no. 5, pp. 653–662, 1954. View at Google Scholar · View at Scopus
  51. A. Gray, E. N. Anionwu, S. C. Davies, and M. Brozovic, “Patterns of mortality in sickle cell disease in the United Kingdom,” Journal of Clinical Pathology, vol. 44, no. 6, pp. 459–463, 1991. View at Google Scholar · View at Scopus
  52. S. T. Miller, L. A. Sleeper, C. H. Pegelow et al., “Prediction of adverse outcomes in children with sickle cell disease,” The New England Journal of Medicine, vol. 342, no. 2, pp. 83–89, 2000. View at Publisher · View at Google Scholar · View at Scopus
  53. E. P. Vichinsky, L. D. Neumayr, A. N. Earles et al., “Causes and outcomes of the acute chest syndrome in sickle cell disease,” The New England Journal of Medicine, vol. 342, pp. 1855–1865, 2000. View at Google Scholar
  54. Noreen kassem. Systems of the Body Affected by Sickle Cell Anemia, http://www.livestrong.com/.
  55. P. F. Milner and M. Brown, “Bone marrow infarction in sickle cell anemia: correlation with hematologic profiles,” Blood, vol. 60, no. 6, pp. 1411–1419, 1982. View at Google Scholar · View at Scopus
  56. E. P. Vichinsky, C. M. Haberkern, L. Neumayr et al., “A comparison of conservative and aggressive transfusion regimens in the perioperative management of sickle cell disease,” The New England Journal of Medicine, vol. 333, no. 4, pp. 206–213, 1995. View at Publisher · View at Google Scholar · View at Scopus
  57. M. A. Leong, C. Dampier, L. Varlotta, and J. L. Allen, “Airway hyperreactivity in children with sickle cell disease,” Journal of Pediatrics, vol. 131, no. 2, pp. 278–285, 1997. View at Publisher · View at Google Scholar · View at Scopus
  58. M. P. Samuels, V. A. Stebbens, S. C. Davies, E. Picton-Jones, and D. P. Southall, “Sleep related upper airway obstruction and hypoxaemia in sickle cell disease,” Archives of Disease in Childhood, vol. 67, no. 7, pp. 925–929, 1992. View at Google Scholar · View at Scopus
  59. D. Powars, J. A. Weidman, T. Odom-Maryon, J. C. Niland, and C. Johnson, “Sickle cell chronic lung disease: prior morbidity and the risk of pulmonary failure,” Medicine, vol. 67, no. 1, pp. 66–76, 1988. View at Google Scholar · View at Scopus
  60. W. F. Rosse, D. Gallagher, T. R. Kinney et al., “Transfusion and alloimmunization in sickle cell disease,” Blood, vol. 76, no. 7, pp. 1431–1437, 1990. View at Google Scholar · View at Scopus
  61. K. E. King, R. S. Shirey, M. W. Lankiewicz, J. Young-Ramsaran, and P. M. Ness, “Delayed hemolytic transfusion reactions in sickle cell disease: simultaneous destruction of recipients' red cells,” Transfusion, vol. 37, no. 4, pp. 376–381, 1997. View at Google Scholar · View at Scopus
  62. K. M. Sullivan, E. Agura, C. Anasetti et al., “Chronic graft-versus-host disease and other late complications of bone marrow transplantation,” Seminars in Hematology, vol. 28, no. 3, pp. 250–259, 1991. View at Google Scholar · View at Scopus
  63. N. Jay, M. James, B. Andrew, B. Simon, R. R. Andrew, and G. I. Nicholas, “Sickle cell and renal transplant: a national survey and literature review,” Experimental and Clinical Transplantation, vol. 10, no. 1, pp. 1–7, 2013. View at Google Scholar