Outcome and Challenges of Kidney Transplant in Patients with Sickle Cell Disease

Table 1

Outcomes of kidney transplant in sickle cell disease patient.

Author	outcome
Chatterjee (1980) [24]	1-year patient survival 86%; 1-year graft survival 67% mortality 1st year 13%; Increased sickle cell crisis
Barber et al. (1987) [22]	1-year graft survival 25%; Crises in 75%
Miner et al. (1987) [27]	Recurrent nephropathy
Chatterjee (1987) [25]	1-year patient survival 88%; 1-year graft survival 82% in live, 62% in cadaveric,; Increased sickle cell crisis
Montgomery et al. (1994) [23]	1-year patient and graft survival 100%; Increased sickle cell crisis
Warady and Sullivan (1998) [29]	1-year graft survival 89%; 2-year graft survival 71%; Patient survival 89%
Ojo et al. (1999) [31]	Delayed function 24%; Acute rejection 26%; 1-year graft survival 78%; 3-year graft survival 46%; 1-year patient survival 78%; 3-year patient survival 59%; Median survival 33 months; Recurrent nephropathy
Bleyer et al. (2001) [28]	1-year patient survival 90.5%; 3-year patient survival 75.0%; 1-year graft 82.5%; 3-year graft survival 53.8%
Abbott et al. (2002) [8]	Risk of mortality same as in transplanted non sickle cell disease
O'Rourke et al. (2008) [32]	Recurrent allograft dysfunction from vascular congestion and tubular necrosis
Scheinman (2009) [33]	10-year patient survival 56%
Kim et al. (2011) [34]	Intragraft sickle cell vasoocclusive crisis as a cause of early allograft loss