Neutrophil Gelatinase-Associated Lipocalin in Kidney Transplantation Is an Early Marker of Graft Dysfunction and Is Associated with One-Year Renal Function

Table 7

Significant factors associated with serum creatinine at one year after kidney transplantation.

	Regression coefficient adjusted*	𝑃-value	95% CI
Model with uNGAL at day 4
Donor gender (male versus female)	0.042	0.004	0.015–0.069
Donor age (years)	0.011	0.008	0.003–0.020
uNGAL4 (ln, ng/mL)	0.067	0.045	0.002–0.132
Model with uNGAL at day 7
Time on dialysis (ln, ng/mL)	0.042	0.004	0.015–0.069
Donor age (years)	0.018	0.002	0.008–0.029
uNGAL7 (ln, ng/mL)	0.138	0.007	0.041–0.235

Note: results given by multiple linear regression; serum creatinine (ln) at 12 months as the dependent variable. Only the significant variables associated with serum creatinine are displayed. Abbreviations: uNGAL: urinary neutrophil gelatinase-associated lipocalin.
*Adjusted for donor status, donor age, recipient age and gender, pretransplant time on dialysis, rehospitalizations, and acute rejection episodes throughout the first year.