Clinical Study

Adjuvant Ciprofloxacin for Persistent BK Polyomavirus Infection in Kidney Transplant Recipients

Table 3

Effect of ciprofloxacin on BKV infection.

  Patient 1Patient 2Patient 3Patient 4Patient 5Patient 6Patient 7Patient 8Patient 9

Viruria (copies/mL)Before ciprofloxacin2 * 1064600 * 106110 * 10614 * 1061300 * 106>500 * 106160 * 106170 * 1062 * 106
Month 3101530 * 1067 * 1069 * 1063100 * 106>500 * 106357 * 106330 * 10644 * 106
ClearanceYes>50%>50%NoNoNoNoNoNo

Viremia (copies/mL)Before ciprofloxacin8305005400137006300093900850010700500
Month 3000160016700041100400073003700
ClearanceYesYesYes>50%No>50%>50%NoNo

BVKANYesYesYesNoYesNoYesYesYes

BKV: BK polyomavirus; BKVAN: BK polyomavirus associated nephropathy.