Research Article

Preconditioning Serum Levels of Endothelial Cell-Derived Molecules and the Risk of Posttransplant Complications in Patients Treated with Allogeneic Stem Cell Transplantation

Table 1

Clinical and biological characteristics of allotransplanted patients included in the study.

Age (years, median, and range)43 (18–63)
Gender
 Males38
 Females18
Diagnosis
 AML33
 B-ALL11
 T-ALL4
 MDS2
 CMML2
 CML1
 Myelofibrosis secondary to polycythemia vera1
 Aplastic anemia2
Status at the time of transplantation
 First complete hematological remission 41
 Second or later complete remission8
 Previous allogeneic stem cell transplantation and
 now complete remission
1
 Detectable disease 6
Conditioning therapy
 Busulfan + cyclophosphamide52
 Total body irradiation + cyclophosphamide1
 Antithymocyte globulin + cyclophosphamide2
 BEAM (carmustine, etoposide, cytarabine, and
 melphalan)
1
Stem cell grafts
 Peripheral blood mobilized stem cells54
 Bone marrow2
GVHD prophylaxis with cyclosporin A plus methotrexate
 4 methotrexate injections34
 3 methotrexate injections21
 2 methotrexate injections1
GVHD, organ affection, and severity
 Skin17
 Liver 3
 Gastrointestinal6
 Grade 15
 Grade 29
 Grade 32
 Grade 42