Table 1: Time evolution of demographic characteristics in 1784 transplantations performed from 1983 to 2014.

Transplant years1983–19911992–19971998–20032004–20092010–2014 value Number of missing values

Number of grafts421385346353279 <19981998

RecipientMale gender60.861.861.962.962.00.99
Age (y)35.8 ± 9.739.1 ± 11.146.7 ± 12.450.6 ± 12.453.1 ± 12.8<0.001
Regrafting20.217.126.313.615.1<0.001
Duration of regular dialysis (y)3.5 ± 3.03.7 ± 3.04.1 ± 4.63.1 ± 2.93.5 ± 3.10.007
History of diabetes1.104.011.915.1<0.001
History of cardiovascular disease4.86.510.422.413.6<0.001
Peak (>50% PRA) sensitization20.76.89.28.26.1<0.001
Delayed graft function (DGF)48.717.716.511.04.7<0.001
Perioperative saline loading0100100100100<0.001
Use of mycophenolate mofetil04.983.592.198.9<0.001
Immunoglobulin induction56.595.378.692.998.9<0.001
ARE occurring during DGF period27.310.75.86.33.6<0.001
 Biopsy proven79.890.494.294.696.8<0.001
Residual diuresis (<500 mL/24 h)69.066.564.551.352.3<0.001 267127
BMI (kg/m2)22.7 ± 3.823.9 ± 3.624.5 ± 4.325.2 ± 4.725.3 ± 4.8<0.001 271126

DonorMale gender60.962.259.558.450.50.024
Age (y)52.4 ± 14.337.5 ± 14.442.7 ± 16.044.0 ± 15.148.8 ± 13.0<0.001
Donation after cardiac death001.22.713.6<0.001
Traumatic cause of death57.945.740.834.927.2<0.001 11 8
Terminal serum creatinine (mg/dL)1.00 ± 0.390.95 ± 0.360.91 ± 0.330.77 ± 0.310.70 ± 0.25<0.001 43 51
BMI (kg/m2)23.2 ± 4.023.7 ± 3.524.7 ± 4.224.9 ± 4.625.6 ± 4.3<0.001 132 131

TransplantIschaemia times
 Cold (h)27.3 ± 7.622.8 ± 6.218.8 ± 6.017.2 ± 5.016.3 ± 5.5<0.001 0 2
 Warm (min)34.2 ± 7.933.0 ± 7.833.2 ± 8.330.0 ± 7.532.6 ± 9.0<0.001 0 2
Number of HLA-A+B+DR mismatches2.6 ± 1.52.2 ± 1.32.7 ± 1.32.5 ± 1.22.6 ± 1.1<0.001

Nominal variables are expressed as percent of total grafts and numerical variables as mean ± standard deviation.
PRA: panel reactive antibodies;  ARE: acute rejection episode;  BMI: body mass index.