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Journal of Transplantation
Volume 2015, Article ID 831501, 8 pages
http://dx.doi.org/10.1155/2015/831501
Research Article

Breakdown in the Organ Donation Process and Its Effect on Organ Availability

1Health Policy and Management, University of Pittsburgh Graduate School of Public Health, 130 DeSoto Street, A724B, Pittsburgh, PA 15261, USA
2Health Policy and Management, University of Pittsburgh Graduate School of Public Health, 130 DeSoto Street, A616, Pittsburgh, PA 15261, USA
3Critical Care, Medicine and Health Policy, University of Pittsburgh School of Medicine, 3550 Terrace Street, Pittsburgh, PA 15261, USA
4Health Policy and Management, University of Pittsburgh Graduate School of Public Health, 130 DeSoto Street, Pittsburgh, PA 15261, USA

Received 31 December 2014; Accepted 13 March 2015

Academic Editor: Trevor Williams

Copyright © 2015 Manik Razdan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. This study examines the effect of breakdown in the organ donation process on the availability of transplantable organs. A process breakdown is defined as a deviation from the organ donation protocol that may jeopardize organ recovery. Methods. A retrospective analysis of donation-eligible decedents was conducted using data from an independent organ procurement organization. Adjusted effect of process breakdown on organs transplanted from an eligible decedent was examined using multivariable zero-inflated Poisson regression. Results. An eligible decedent is four times more likely to become an organ donor when there is no process breakdown (adjusted OR: 4.01; 95% CI: 1.6838, 9.6414; ) even after controlling for the decedent’s age, gender, race, and whether or not a decedent had joined the state donor registry. However once the eligible decedent becomes a donor, whether or not there was a process breakdown does not affect the number of transplantable organs yielded. Overall, for every process breakdown occurring in the care of an eligible decedent, one less organ is available for transplant. Decedent’s age is a strong predictor of likelihood of donation and the number of organs transplanted from a donor. Conclusion. Eliminating breakdowns in the donation process can potentially increase the number of organs available for transplant but some organs will still be lost.