Liver Transplantation for Hepatocellular Carcinoma: A Single Center Resume Overlooking Four Decades of Experience

Figure 6

HCC recurrence with respect to tumor morphology and neoadjuvant therapy. The effectiveness as estimated by rate of HCC recurrences was analysed with respect to different neoadjuvant therapy regimen and tumor morphology. Hospital deaths and treatment groups with were excluded from analysis. Thus, only surgery remained for estimation of cumulative HCC recurrence in the group of nondetectable tumors (a). In the group of uninodular HCC (b) there was no significant difference in HCC recurrence rates comparing the mono- and multimodular pretreatments. Multinodular/unilateral HCC (c) had a significantly lower rate of HCC recurrence (Log Rank ) if treated by PEI, while TACE did not make a difference for this group of tumors at all (Log Rank ). In multinodular/bilateral tumors (d) TACE was significantly better as compared to PEI (Log Rank ). The PEI group had the same cumulative rate of HCC recurrence as the no-treatment group.

(a)

(b)

(c)

(d)