Temporal Changes on the Risks and Complications of Posttransplantion Diabetes Mellitus Following Cardiac Transplantation

Table 2

Univariate and multivariate analysis for the risk factors related with the development of PTDM at 1 year.

	Univariate analysis		Multivariate analysis
Parameters	Hazard Ratio [95% Confidence limits]	p value	Hazard Ratio [95% Confidence limits]	p value
Donor age	1.017 [1.000, 1.034]	0.0446
Recipient age (+10 years)	1.27 [1.025, 1.574]	0.0292	1.302 [1.046, 1.621]	0.0182
Recipient BMI	1.060 [1.000, 1.124]	0.0510
Hyperlipidaemia	1.445 [0.921, 2.269]	0.1094
Cold ischemic time (+20 min)	1.100 [1.009, 1.199]	0.0303	1.110 [1.012, 1.216]	0.0268
Tacrolimus	2.52 [1.57, 4.05]	<0.0001	3.378 [2.063, 5.530]	<0.0001
Furosemide	1.612 [0.959, 2.710]	0.0714	2.048 [1.185, 3.541]	0.0103
Thiazide diuretics	0.344 [0.084, 1.400]	0.1362
Year of transplant		0.0711
1983 to 1992	0.618 [0.357, 1.071]	0.0863
1993 to 2002	0.549 [0.318, 0.945]	0.0305
2003 to 2011	- - -	- - -
Gender mismatch		0.1072
No mismatch	- - -	- - -
Female recipient/Male	0.342 [0.107, 1.091]	0.0699
donor
Male recipient/Female	0.682 [0.375, 1.243]	0.2116
donor