Analogs of LDL Receptor Ligand Motifs in Dengue Envelope and Capsid Proteins as Potential Codes for Cell Entry

Figure 5

Dual label HeLa cell binding experiments using Dsp2EP-FITC and LDL-CM-DiI. Overlay (A) shows images of Dsp2EP-FITC (green) and LDL-CM-DiI (red) fluorescence images. Loci 1, 2, and 3 indicated in frame (A) are shown as enlarge images in frames 1, 2, and 3, respectively. Signals in locus frame 1 appear in three distinct colors, yellow, pink, and green. Red is the predominant signal in locus (A)2, frame 2, while green signal is seen in locus (A)3, frame 3. Image J was used to separate green and red signals, rendered in 3D in corresponding frames 1R and 1G, 2R and 2G, and 3R and 3G, respectively.