Table 1: Probiotic strains used against Schistosoma mansoni infection in mice.

Probiotics strainDose/routeMechanismsAntiparasitic effectReferences

Zymomonas mobilis1 × 109 CFU/mL orally, at a dose of 0.3 mL/dayProvoke a secondary
immune response
A 61% protection from the infection was observed in
the treated group

Probiotic labneh containing streptococcus salivarius subsp. thermophilus, Lactobacillus delbrueckii subsp. Bulgaricus and DVS-ABT2Probiotic labneh and garlic and onions fed for 21 days before and 45 days after infectionImproving intestinal balance50%–66% reduction in worm burden; 70% and 56.44% egg count reduction in liver and intestine, respectively[18]

Lactobacillus casei B-444; Lactobacillus plantarum B-531; Lactobacillus reuteriB-14141 and Lactobacillus acidophilus1 × 106 CFU each mixed with feedA significant stimulation for IgM response against SWAP before and
after infection
Increased IgM; A decrease in the activity of AST, LDH and GT[19]

Lactobacillus sporogenes12.5 million
spores/mice/week for 8 weeks orally
Decreased cytokine-induced chromosomal aberrations and DNA damageSignificant reduction in
chromosomal aberrations

Lactobacillus sporogenes12.5 million spores/mice/week for 8 weeks orally from the first day of infectionReduced DNA damage; ameliorates the hepatic and intestinal damageReduced worm and egg count[21]

SWAP: soluble worm antigen preparation, AST: aspartate transaminase, ALT: alanine transaminase, LDH: lactate dehydrogenase, γGT: gamma-glutamyl transferase, DVS-ABT2: containing Streptococcus thermophilus, Lactobacillus acidophilus, and Bifidobacterium bifidum, and CFU: colony forming units.