Research Article

Mutated KRAS Is an Independent Negative Prognostic Factor for Survival in NSCLC Stage III Disease Treated with High-Dose Radiotherapy

Table 1

Baseline characteristics in the whole study population and the subset with tissue specimen available.

RAKETSatellite
Main studyExamined groupMain studyExamined group

=151357134
Median age62 (43–78)61 (49–78)62 (42–81)62 (43–76)
Gender F/M48/52%46/54%51/49%53/47%
PS 0/155/45%40/60%62/38%65/35%
Stage IIIA/IIIB34/66%29/71%37/62%24/76%
Weight loss > 5%17%26%37%32%
FEV12.1 (0.8–4.5)2.2 (0.9–4.3)2.2 (1.1–3.7)2.1 (1.1–3.7)
Histology:
 Adenocarcinoma48%63%49%44%
 SCC32%26%39%44%
 NSCLC NOS20%11%12%12%