Research Article
Simple and Objective Prediction of Survival in Patients with Lung Cancer: Staging the Host Systemic Inflammatory Response
Table 5
The relationship between parameters and survival in patients with mGPS = 1
.
| | Parameter | Patients | Univariate | Multivariate | | HR (95% CI) | value | HR (95% CI) | value |
| | Age | | | | | | | <60/60–69/70–79/≥80 | 33/71/89/28 | 1.24 (1.09–1.40) | 0.001 |
— | — | | Sex | | | | | | | Male | 174 | 1 | 0.171 | — | — | | Female | 130 | 0.84 (0.66–1.08) | — | — | — | | Centre | | | | | | | Aberdeen | 145 | 1 | 0.425 | — | — | | Fife | 23 | 0.89 (0.55–1.43) | — | — | — | | Stobhill | 55 | 0.99 (0.72–1.36) | — | — | — | | Inverclyde | 67 | 1.23 (0.92–1.66) | — | — | — | | Deprivation (quintile) (most deprived = 1, least deprived = 5) | | | | | | | 1/2/3/4/5 | 75/47/75/77/30 | 0.99 (0.90–1.08) | 0.777 | — | — | | Smoking history (NS = never smoker, otherwise pack years) | | | | | | | NS/<20/20–60/>60 | 11/33/177/69 | 1.02 (0.86–1.22) | 0.792 | — | — | | Performance status | | | | | | | 0/1/2/3/4 | 26/130/105/40/3 | 1.83 (1.57–2.14) | <0.001 | 1.81 (1.55–2.13) | <0.001 | | Weight loss (% body weight) | | | | | | | 0/<5/5–10/>10 | 181/48/53/22 | 1.15 (1.06–1.25) | 0.001 | — | — | | FEV1 (%) | | | | | | | >80/80–60/59–40/<40 | 138/31/45/7 | 0.94 (0.83–1.06) | 0.313 | — | — | | Local symptoms | | | | | | | No/yes | 18/222 | 1.60 (0.91–2.80) | 0.105 | — | — | | Stage | | | | | | | NSCLC | | | | | | | I/II/IIIa/IIIb/IV | 15/19/20/56/84 | 1.31 (1.19–1.45) | <0.001 | 1.08 (1.03–1.13) | 0.002 | | SCLC | | | | | | | Limited/extensive | 10/32 | 0.51 (0.23–1.11) | 0.091 | — | — | | Treatment | | | | | | | Radical | | | | | | | BSC/surgery/RT | 43/17/15 | 0.55 (0.41–0.72) | <0.001 | 0.70 (0.52–0.94) | 0.017 | | Palliative | | | | | | | Chemo/RT/BSC | 107/58/55 | 1.07 (0.90–1.26) | 0.436 | — | — |
|
|
