Alterations in Gene Expression of Components of the Renin-Angiotensin System and Its Related Enzymes in Lung Cancer

Figure 2

Expression of genes of proteins that comprise the classical renin-angiotensin system. Gene expression in normal lung tissue (open bars ) and lung tumor tissue (solid bars, ) is expressed as Log2 values. AGT encodes angiotensinogen, REN encodes renin, ACE encodes angiotensin-converting enzyme, AGTR1 encodes the AT₁ Ang II receptor subtype, and AGTR2 encodes the AT₂ Ang II receptor subtype. by unpaired test with Welch’s correction for heterogeneity of variance and Sidak’s correction for multiple comparisons, by unpaired test with Welch’s correction for heterogeneity of variance and Sidak’s correction for multiple comparisons.