Influence of Methylenetetrahydrofolate Reductase C677T, A1298C, and G80A Polymorphisms on the Survival of Pediatric Patients with Acute Lymphoblastic Leukemia

Table 1

Characteristics of the patients to ALL according to genotypes of the C677T, A1298C, and G80A polymorphisms.

	𝑛=126			𝑛=118			𝑛=118
	677 CC (%)	677 CT (%)	677 TT (%)	1298 AA (%)	1298 AC (%)	1298 CC (%)	80 AA (%)	80 GA (%)	80GG (%)
Gender	71	46	9	50	43	25	42	51	25
Male	32 (25.4)	24 (19.0)	5 (04.0)	25 (21.2)	17 (14.5)	12 (10.1)	21 (17.8)	20 (17.0)	13 (11.0)
Female	39 (31.0)	22 (17.4)	4 (03.2)	25 (21.2)	26 (22.0)	13 (11.0)	21 (17.8)	31 (26.3)	12 (10.1)
Age
<9 years	37 (29.4)	23 (18.2)	4 (03.2)	20 (17.0)	27 (22.9)	17 (14.5)	19 (16.1)	31 (26.3)	14 (11.8)
≥9 years	34 (27.0)	23 (18.2)	5 (04.0)	30 (25.4)	16 (13.5)	8 (06.7)	23 (19.5)	20 (17.0)	11 (09.3)
Living	52 (41.3)	34 (27.0)	7 (05.5)	40 (33.9)	30 (25.4)	19 (16.1)	31 (26.3)	42 (35.6)	18 (15.3)
Dead	19 (15.1)	12 (09.5)	2 (01.6)	10 (08.5)	13 (11.0)	6 (05.1)	11 (09.3)	9 (07.6)	7 (05.9)
Ratio (L/A)^‡	0.36	0.35	0.28	0.25	0.43	0.31	0.35	0.21	0.39

^‡𝑃 value significant; L: living; D: dead.