Retinoid Differentiation Therapy for Common Types of Acute Myeloid Leukemia

<table>Inhibition of the activity of GSK-3<i>β</i> is important for ATRA sensitivity, The figure shows one way in which activity of GSK-3<i>β</i> affects ATRA responsiveness of myeloid cells and how transcriptional activity of RAR<i>α</i> and kinase activity of GSK-3<i>β</i> are linked <i>via</i> ATRA-related inhibitory phosphorylation (P) of GSK-3<i>β</i>.</table>

Leukemia Research and Treatment

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Figure 2

Figure 2: Retinoid Differentiation Therapy for Common Types of Acute Myeloid Leukemia 