An Unusual Presentation of Liver Failure in a Patient with Primary Gastrointestinal Hodgkin's Lymphoma
Figure 2
(a) H&E stain of liver biopsy showing a mixed inflammatory infiltrate within the portal tract comprised of neutrophils, plasma cells, histiocytes, and scattered lymphocytes without definitive Hodgkin’s or Reed-Sternberg cells. A damaged bile duct with intraepithelial lymphocytes and periductular neutrophils is shown (arrow). (b) Immunostaining for cytokeratins AE1-3 highlights the damaged bile duct as well as ductular proliferation at the portal tract periphery. (c) A portal tract representative of those assessed as lacking interlobular bile ducts showing the same mixed inflammatory infiltrate as above and no discernable interlobular bile ducts. (d) However, AE1-3 highlights peripheral ductular proliferation in this tract.
