Analysis of NF-𝜿B Pathway Proteins in Pediatric Hodgkin Lymphoma: Correlations with EBV Status and Clinical Outcome—A Children's Oncology Group Study

Figure 4

Spearman correlation coefficients between NF-𝜅B pathway proteins stratified by EBV status (A) and rapidity of response to therapy (B) Nuclear (a), (b) and cytoplasmic (c), (d) NF-𝜅B pathway protein correlations were examined in EBV- patients (left panels) and EBV+ patients (right panels). Significant results are shown in white with raw 𝑃 values; 𝑃 values after correction for multiple comparisons are noted with asterisks (*𝑃<0.05, **𝑃<0.01). Full data set with Spearman correlation coefficients are shown in Supplemental Figure 3. (B) Nuclear (a), (b) and cytoplasmic (c), (d) NF-𝜅B pathway protein correlations were examined in patients with rapid early response (RER) to ABVE-PC (left panels) versus those with a slow early response (SER) to the same therapy (right panels). Full datasets with Spearman correlation coefficients are shown in Supplemental Figure 4.