Antitumor Activity of the Carboplatin-α-Cyclodextrin Adduct

Liu, Weiping; Xiong, Huizhou; Yang, Yikun; Li, Ling; Shen, Zhiqiang; Chen, Zhihe

doi:https://doi.org/10.1155/MBD.1997.305

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Volume 4 | Article ID 431870 | https://doi.org/10.1155/MBD.1997.305

Antitumor Activity of the Carboplatin-α-Cyclodextrin Adduct

Weiping Liu,¹Huizhou Xiong,¹Yikun Yang,¹Ling Li,²Zhiqiang Shen,²and Zhihe Chen²

Received19 Aug 1997

Accepted11 Sept 1997

Abstract

Antitumor activity of the adduct between Carboplatin and α-cyclodextrin has been tested against Sarcoma 180 (S180) and Ehrlich ascites carcinoma (EAC) murine tumors. The preliminary toxicity has also been evaluated by histological examinations of the treated animals. The results show the adduct has less antitumor efficacy than and similar toxicity to Carboplatin.

Copyright

Copyright © 1997 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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