Table of Contents
Metal-Based Drugs
Volume 4 (1997), Issue 4, Pages 193-197
http://dx.doi.org/10.1155/MBD.1997.193

Di-n-Butyl-, Tri-n-Butyl- and Triphenyltin dl-Terebates: Synthesis, Characterization and In Vitro Antitumour Activity

1Department of General and Organic Chemistry, Faculty of Applied Sciences, Free University of Brussels V.U.B., Pleinlaan 2, Brussels B-1050, Belgium
2High Resolution NMR Centre, Free University of Brussels V.U.B., Pleinlaan 2, Brussels B-1050, Belgium
3Department of Chemistry, Northwest University, ShaanXi, Xian 710 069, China

Received 25 April 1997; Accepted 6 May 1997

Copyright © 1997 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Di-n-butyltin, tri-n-butyltin and triphenyltin terebates were screened against several human tumour cell lines and found comparably or more active than carboplatin, cis-platin, 5-fluorouracil, methotrexate and doxorubicin, some reference compounds used clinically.