Metal-Based Drugs

Metal-Based Drugs / 2002 / Article

Open Access

Volume 8 |Article ID 196271 | https://doi.org/10.1155/MBD.2002.283

M. Kidwai, R. Venkataramanan, B. Dave, "Antifungal Activity of Solventlessly Synthesized Organomercurials", Metal-Based Drugs, vol. 8, Article ID 196271, 3 pages, 2002. https://doi.org/10.1155/MBD.2002.283

Antifungal Activity of Solventlessly Synthesized Organomercurials

Received21 Jan 2002
Accepted04 Feb 2002

Abstract

A series of new barbituryl/thiobarbituryl substituted organomercurial derivatives 3a-i have been synthesised from pyrimidine derivatives 1a-c and arylmercuric chloride 2a-c over K2CO3 under microwave irradiations (MWI). This solventless synthesis apart from eliminating organic solvent from workup step, also gave improved yield as compared to the conventional heating, with reaction time reduced from hours to minutes. The prepared compounds were tested against A.niger¯ and A.flavous¯ for their antifungal activity and were found to posses good activity.

Copyright © 2002 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


More related articles

 PDF Download Citation Citation
 Order printed copiesOrder
Views53
Downloads15
Citations

Related articles

We are committed to sharing findings related to COVID-19 as quickly as possible. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Review articles are excluded from this waiver policy. Sign up here as a reviewer to help fast-track new submissions.