The In Vitro Antitumour Activity of Novel, Mitochondrial-Interactive, Gold-Based Lipophilic Cations

Table 2

Mean drug concentration (𝜇M) causing 50% cell death (IC₅₀) after treatment of various cell lines with the five experimental compounds.

Cell lines	[A]^1	[B]	[C]	[D]
MCF-7	2.31	20.327	5.33	6.508
MCF-12A	2.424	160	25.639	16.58
A2780	1.158	22.244	12.996	17.277
A2780cis	2.58	37.663	10	20
HeLa	1.407	63.793	11.476	12.264
CoLo	7.686	200	31.141	26.234
Primary fibroblasts	0.887	170	11.874	8.046
B16	0.115	49.89	4.999	2.738

¹ Average of 3–5 experiments.