Research Article

The In Vitro Antitumour Activity of Novel, Mitochondrial-Interactive, Gold-Based Lipophilic Cations

Table 4

Mitochondria of MCF-7 and MCF-12A cells with undamaged membranes after treatment with experimental compounds.

Percentage mitochondria with undamaged membranes
calculated as the invert of the percentage cytochrome c release1

Cell lineUntreated[A][B][C][D]

MCF-760.75361.7539.541.0
MCF-12A70.252.2576.548.046.25

1Average of 3–5 experiments.