Synthesis, Structure, Electrochemistry, and Cytotoxic Properties of Ferrocenyl Ester Derivatives

Table 2

Cytotoxicities of ferrocenes studied on HT-29 colon cancer and MCF-7 breast cancer cell lines at 72 hours, as determined by MTT assay. IC values are the average of four independent measurements with their standard deviations ().

	HT-29	MCF-7
Complex	IC50 (𝜇M)	IC50 (𝜇M)
FeCp2	360(30)	1500(100)
Fe(Cp–COOEt)2	370(10)	250(20)
Fe(Cp–COOMe)(Cp–COOEt)	500(20)	320(30)
Fe(Cp–COOMe)2	720(50)	520(20)
Fe(CpCOOCH2 CH2OH)2	370(20)	340(30)
Fe(CpCOCH2CHCH2 )2	180(10)	190(30)
Fe[Cp2]BF4	180(10)	150(05)