Table of Contents
Molecular Biology International
Volume 2011 (2011), Article ID 256063, 6 pages
http://dx.doi.org/10.4061/2011/256063
Review Article

Relationship between DNA Mismatch Repair Deficiency and Endometrial Cancer

Department of Obstetrics and Gynecology, Keio University School of Medicine, Shinanomachi 35 Shinjuku-Ku, Tokyo 160-8582, Japan

Received 28 January 2011; Revised 25 August 2011; Accepted 20 September 2011

Academic Editor: Mark Berneburg

Copyright © 2011 Kenta Masuda et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. Jemal, R. Siegel, E. Ward, Y. Hao, J. Xu, and M. J. Thun, “Cancer statistics,” CA: A Cancer Journal for Clinicians, vol. 59, no. 4, pp. 225–249, 2009. View at Publisher · View at Google Scholar · View at Scopus
  2. H. Hampel, W. Frankel, J. Panescu et al., “Screening for Lynch syndrome (hereditary nonpolyposis colorectal cancer) among endometrial cancer patients,” Cancer Research, vol. 66, no. 15, pp. 7810–7817, 2006. View at Publisher · View at Google Scholar · View at Scopus
  3. H. T. Lynch and A. J. Krush, “The cancer family syndrome and cancer control,” Surgery Gynecology and Obstetrics, vol. 132, no. 2, pp. 247–250, 1971. View at Google Scholar · View at Scopus
  4. H. T. Lynch and J. F. Lynch, “Hereditary nonpolyposis colorectal cancer,” Seminars in Surgical Oncology, vol. 18, no. 4, pp. 305–313, 2000. View at Google Scholar · View at Scopus
  5. K. E. Resnick, H. Hampel, R. Fishel, and D. E. Cohn, “Current and emerging trends in Lynch syndrome identification in women with endometrial cancer,” Gynecologic Oncology, vol. 114, no. 1, pp. 128–134, 2009. View at Publisher · View at Google Scholar · View at Scopus
  6. H. F. A. Vasen, J. P. Mecklin, P. M. Khan, and H. T. Lynch, “The international collaborative group on hereditary non-polyposis colorectal cancer,” Diseases of the Colon and Rectum, vol. 34, no. 5, pp. 424–425, 1991. View at Google Scholar · View at Scopus
  7. H. F. A. Vasen, P. Watson, J. P. Mecklin, and H. T. Lynch, “New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the international collaborative group on HNPCC,” Gastroenterology, vol. 116, no. 6, pp. 1453–1456, 1999. View at Publisher · View at Google Scholar · View at Scopus
  8. T. Jascur and C. R. Boland, “Structure and function of the components of the human DNA mismatch repair system,” International Journal of Cancer, vol. 119, no. 9, pp. 2030–2035, 2006. View at Publisher · View at Google Scholar · View at Scopus
  9. K. Banno, M. Yanokura, Y. Kobayashi et al., “Endometrial cancer as a familial tumor: pathology and molecular carcinogenesis,” Current Genomics, vol. 10, no. 2, pp. 127–132, 2009. View at Publisher · View at Google Scholar · View at Scopus
  10. Y. Muraki, K. Banno, M. Yanokura et al., “Epigenetic DNA hypermethylation: clinical applications in endometrial cancer,” Oncology Reports, vol. 22, no. 5, pp. 967–972, 2009. View at Publisher · View at Google Scholar · View at Scopus
  11. S. N. Westin, R. A. Lacour, D. L. Urbauer et al., “Carcinoma of the lower uterine segment: a newly described association with Lynch syndrome,” Journal of Clinical Oncology, vol. 26, no. 36, pp. 5965–5971, 2008. View at Publisher · View at Google Scholar · View at Scopus
  12. K. Masuda, K. Banno, M. Yanokura et al., “Carcinoma of the lower uterine segment (LUS): clinicopathological characteristics and association with Lynch syndrome,” Current Genomics, vol. 12, no. 1, pp. 25–29, 2011. View at Google Scholar
  13. C. R. Boland, S. N. Thibodeau, S. R. Hamilton et al., “A national cancer institute workshop on microsatellite instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer,” Cancer Research, vol. 58, no. 22, pp. 5248–5257, 1998. View at Google Scholar · View at Scopus
  14. T. Kanaya, S. Kyo, Y. Maida et al., “Frequent hypermethylation of MLH1 promoter in normal endometrium of patients with endometrial cancers,” Oncogene, vol. 22, no. 15, pp. 2352–2360, 2003. View at Publisher · View at Google Scholar · View at Scopus
  15. K. Banno, N. Susumu, T. Hirao et al., “Two Japanese kindreds occurring endometrial cancer meeting new clinical criteria for hereditary non-polyposis colorectal cancer (HNPCC), Amsterdam criteria II,” Journal of Obstetrics and Gynaecology Research, vol. 30, no. 4, pp. 287–292, 2004. View at Publisher · View at Google Scholar · View at Scopus
  16. K. Banno, N. Susumu, M. Yanokura et al., “Association of HNPCC and endometrial cancers,” International Journal of Clinical Oncology, vol. 9, no. 4, pp. 262–269, 2004. View at Publisher · View at Google Scholar · View at Scopus
  17. M. Aarnio, R. Sankila, and H. J. Järvinen, “Cancer risk in mutation carriers of DNA-mismatch-repair genes,” International Journal of Cancer, vol. 81, no. 2, pp. 214–218, 1999. View at Google Scholar · View at Scopus
  18. F. E. M. Rijcken, M. J. E. Mourits, A. G. J. van der Zee, J. H. Kleibeuker, and H. Hollema, “Gynecologic screening in hereditary nonpolyposis colorectal cancer,” Gynecologic Oncology, vol. 91, no. 1, pp. 74–80, 2003. View at Publisher · View at Google Scholar · View at Scopus
  19. I. Dove-Edwin, D. Boks, H. J. W. Thomas et al., “The outcome of endometrial carcinoma surveillance by ultrasound scan in women at risk of hereditary nonpolyposis colorectal carcinoma and familial colorectal carcinoma,” Cancer, vol. 94, no. 6, pp. 1708–1712, 2002. View at Publisher · View at Google Scholar · View at Scopus
  20. F. Lécuru, C. Huchon, and P. L. Puig, “Contribution of ultrasonography to endometrial cancer screening in patients with hereditary nonpolyposis colorectal cancer/Lynch syndrome,” International Journal of Gynecological Cancer, vol. 20, no. 4, pp. 583–587, 2010. View at Publisher · View at Google Scholar · View at Scopus
  21. N. M. Lindor, G. M. Petersen, N. Press et al., “Recommendations for the care of individuals with an inherited predisposition to Lynch syndrome: a systematic review,” Journal of the American Medical Association, vol. 296, no. 12, pp. 1507–1517, 2006. View at Publisher · View at Google Scholar · View at Scopus
  22. A. Auranen and T. Joutsiniemi, “A systemic review of gynecological cancer surveillance in women belonging to hereditary nonpolyposis colorectal cancer (Lynch syndrome) families.,” Acta Obstetricia et Gynecologica Scandinavica, vol. 90, no. 5, pp. 437–444, 2011. View at Publisher · View at Google Scholar
  23. W. Burke, G. Petersen, C. Varricchio et al., “Recommendations for follow-up care of individuals with an inherited predisposition to cancer. I. Hereditary nonpolyposis colon cancer. Cancer genetics studies consortium,” Journal of the American Medical Association, vol. 277, no. 11, pp. 915–919, 1997. View at Google Scholar
  24. K. M. Schmeler, H. T. Lynch, K. H. Lu et al., “Prophylactic surgery to reduce the risk of gynecologic cancers in the Lynch syndrome,” The New England Journal of Medicine, vol. 354, no. 3, pp. 261–269, 2006. View at Publisher · View at Google Scholar · View at Scopus
  25. K. Banno, M. Yanokura, N. Susumu et al., “Relationship of the aberrant DNA hypermethylation of cancer-related genes with carcinogenesis of endometrial cancer,” Oncology reports, vol. 16, no. 6, pp. 1189–1196, 2006. View at Google Scholar · View at Scopus