Priming DNA Replication from Triple Helix Oligonucleotides: Possible Threestranded DNA in DNA Polymerases
Figure 6
Model of interacting bonds with the R strand, which pairs with Watson-Crick bases modified from Zhurkin et al. [35]. (a) show the classical interactions between triple helix and DS DNA with Hoogsteen and reverse Hoogsteen bonds. Shown in (b) the models could account for the displacement of the homologous Watson strand by the primer or the R strand as in recombination with the invaded duplex without mismatches. The most stable triplexes are G: G:C, C: C:G, A: A:T, and T: T:A.
