Genotoxicity Studies Performed in the Ecuadorian Population

Table 1

Cytogenetic findings in genotoxicity studies.

Glyphosate	Paz-y-Miño et al. [6]	Comet assay: 35.5 μm DNA migration for exposed, 25.94 μm for controls.
	Paz-y-Miño et al. [13]	All the studied population showed low or no chromosomal fragility.
Other pesticides	Paz-y-Miño et al. [9, 10, 93]	Chromosomal aberrations: 20.59% in exposed and 2.73% in controls.
	Paz-y-Miño et al. [55]	Comet assay: 31.58 μm DNA migration for exposed, 25.94 μm for controls.; Chromosomal aberrations: 5.48% in exposed and 0.45% in controls.
Hydrocarbons	Paz-y-Miño et al. [7]	Chromosomal aberrations: 20% in exposed and 1-2% in controls.; 12% type A DNA damage and 1% type E DNA damage in exposed group while 81% type A and 0% type E in controls.
	Paz-y-Miño et al. [88]	48.8% type A DNA damage and 0.1% type E DNA damage in exposed group while 67.9% type A and 0% type E in controls.
Radiation	Paz-y-Miño et al. [102]	Chromosomal aberrations: 29% in exposed, 26.0% in the followup, and 3.5% in controls.
	Paz-y-Miño et al. [112]	12.6% metaphases with telomeric associations in the exposed smoker group; 6.0% TA in exposed nonsmokers; 9.0% in unexposed smokers and 0.1% TA in control group.
	Paz-y-Miño et al. [9, 10, 93]	Comet assay: 26.55 μm DNA migration; mean chromosomal aberrations without gaps: 5.39% (𝑟=0.50, 𝑃<0.05). Mean chromosomal aberrations including gaps: 12.08% (𝑟=0.78, 𝑃<0.01).
	Muñoz et al. [128]	Comet assay: 29.08 μm DNA migration for exposed group, 25.91 μm for controls.; Chromosomal aberrations: 50% in exposed, 26.0% in the followup, and 4% in controls.