Table of Contents
Molecular Biology International
Volume 2012 (2012), Article ID 643856, 4 pages
http://dx.doi.org/10.1155/2012/643856
Research Article

Relative Copy Number Variations of CYP2C19 in South Indian Population

1Pharmacogenomics Laboratory, Department of Pharmacology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry 605006, India
2Onco-Hematology Unit, Department of Pediatrics, University Hospital of Geneva, Geneva, Switzerland
3U 763, INSERM, Hopital Robert Debre, Paris, France

Received 29 March 2012; Accepted 28 April 2012

Academic Editor: George A. Calin

Copyright © 2012 Anichavezhi Devendran et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

The amplification plots for CYP2C19, IL-2 gene amplification are depicted in the supplementary figures 1 and 2 (where x-axis represents the cycle number and y-axis represents ΔRn reflecting the magnitude of the signal generated by PCR conditions used for the experiment). The dissociation curves specific for CYP2C19 and IL-2 amplification are given in the supplementary figures 3 and 4 (where x-axis represents temperature in °C and y-axis represents the derivative of fluorescence with respect to temperature). The standard curves for CYP2C19 and IL-2 gene quantification are given in the figures 5 and 6 (where x-axis represents the log transformed concentrations of the standards used and y-axis represents the cycle threshold (Ct) reflecting the cycle number at which the fluorescence generated within a reaction crossing the threshold level.

  1. Supplementary Figures