Research Article

The RASSF1 Gene and the Opposing Effects of the RASSF1A and RASSF1C Isoforms on Cell Proliferation and Apoptosis

Figure 8

RASSF1A and RASSF1C mRNA were assessed in 13 breast tumor tissues and normal tissues using RT-PCR. (a) RASSF1A is downregulated in 92% (12/13) and is upregulated in 8% (1/13); and (b) RASSF1C is downregulated in 15% and is upregulated in 62% (8/13) of the breast tumors assessed. 1A N : relative RASSF1A expression in normal breast tissue. 1A T : relative RASSF1A expression in breast tumor tissue. 1C N : relative RASSF1C expression in normal breast tissue. 1C T : relative RASSF1C expression in breast tumor tissue.
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(a)
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