Mediators of Inflammation

Mediators of Inflammation / 1993 / Article
Special Issue

Supplement 1 August 1993 Carnitine and Congeners as Regulators of Tumour Necrosis Factor Guest Editors - C De Simone, E Arrigoni Martelli and P Foresta

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Research paper | Open Access

Volume 2 |Article ID 716950 |

Giuseppe Famularo, Sonia Tzantzoglou, Gino Santini, Vito Trinchieri, Sonia Moretti, Aleardo Koverech, Claudio De Simone, "L-carnitine: a partner between immune response and lipid metabolism ?", Mediators of Inflammation, vol. 2, Article ID 716950, 4 pages, 1993.

L-carnitine: a partner between immune response and lipid metabolism ?


The authors demonstrated that in vivo administered L-carnitine strongly ameliorated the immune response in both healthy individuals receiving Intralipid and ageing subjects with cardiovascular diseases, as shown by the enhancement of mixed lymphocyte reaction. Notably, in the latter group L-carnitine treatment also resulted in a significant reduction of serum levels of both cholesterol and triglycerides. Therefore, the hypothesis is that L-carnitine supplementation could ameliorate both the dysregulated immune response and the abnormal lipid metabolism in several conditions.

Copyright © 1993 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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