The Role of Cytokines in Inflammatory Bowel Disease

Radford-Smith, G.; Jewell, D. P.

doi:https://doi.org/10.1155/S0962935194000013

Mediators of Inflammation

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Invited review | Open Access

Volume 3 | Article ID 254314 | https://doi.org/10.1155/S0962935194000013

The Role of Cytokines in Inflammatory Bowel Disease

G. Radford-Smith¹and D. P. Jewell¹

Received30 Nov 1993

Accepted30 Nov 1993

Abstract

Cytokines play an important role in the development and persistence of the inflammatory lesions seen in Crohn's disease and ulcerative colitis. This review discusses the current thinking of the role of cytokines in chronic intestinal inflammation including the involvement of immunoregulatory cytokines within the Th1 and Th2 subsets.

Copyright

Copyright © 1994 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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