Abstract
The angiogenic factors vascular endothelial growth factor (VEGF)
and placenta growth factor (PlGF) are respectively up- and
downregulated by hypoxia. We aimed to study circulating levels of
the above factors in intrauterine growth restriction (IUGR) and to
correlate their levels with the customized centiles of the
infants. The study included 25 IUGR and 25 appropriate for
gestational age (AGA) full-term, singleton infants and their
mothers. Maternal (MS), fetal (UC), and neonatal day 1 (N1) and 4
(N4) blood was examined. MS and N1 PlGF, as well as UC VEGF levels
correlated with the customized centiles of the infants (