Mediators of Inflammation

Mediators of Inflammation / 2005 / Article

Open Access

Volume 2005 |Article ID 846930 |

Unase Buyukkocak, Fatma Caglayan, Osman Caglayan, Murat Basar, Murat Cakmak, Ertan Batislam, Sevgi Ulusoy, "Anaesthesia and the Acute Phase Protein Response in Children Undergoing Circumcision", Mediators of Inflammation, vol. 2005, Article ID 846930, 4 pages, 2005.

Anaesthesia and the Acute Phase Protein Response in Children Undergoing Circumcision

Received08 Jun 2005
Accepted22 Jun 2005


Concentrations of acute phase proteins (CRP: C-reactive protein, albumin) change during surgery. We investigated the acute phase response to circumcision and the effects of anaesthesia on this response. The children were divided into four groups; group 1 (intratracheal general anaesthesia, n=40), group 2 (general anaesthesia with mask, n=20), group 3 (ketamine, n=20), group 4 (local anaesthesia, n=35). Blood samples were obtained, 24 hours before circumcision, after premedication, and 24 hours after circumcision. CRP and albumin before circumcision were comparable for all groups. There was no increase in CRP, and albumin remained steady throughout the study. No difference was observed among the groups, and related to anaesthesia. No responsiveness may be explained with the size of injured tissue or anatomical and histological type of preputium.

Copyright © 2005 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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