Table of Contents Author Guidelines Submit a Manuscript
Mediators of Inflammation
Volume 2006 (2006), Article ID 24827, 6 pages
Research Communication

Unexpected Smoking-Linked High MMP-9 in Induced Sputum of Hazardous Dust-Exposed Workers

1Occupational and Environmental Health Center, Clalit Health Services, Tel-Aviv, Israel
2The Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv 69978, Israel
3National Lab Service for ILD, Institute of Pulmonary and Allergic Diseases, Tel-Aviv Sourasky Medical Center, Tel-Aviv 64239, Israel

Received 13 October 2005; Accepted 12 December 2005

Copyright © 2006 Yehuda Lerman et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. G S Warshamana, D A Pociask, P Sime, D A Schwartz, and A R Brody, “Susceptibility to asbestos-induced and transforming growth factor-β1-induced fibroproliferative lung disease in two strains of mice,” American Journal of Respiratory Cell and Molecular Biology, vol. 27, no. 6, pp. 705–713, 2002. View at Google Scholar
  2. L A Ortiz, J Lasky, G Lungarella et al., “Upregulation of the p75 but not the p55 TNF-a receptor mRNA after silica and bleomycin exposure and protection from lung injury in double receptor knockout mice,” American Journal of Respiratory Cell and Molecular Biology, vol. 20, no. 4, pp. 825–833, 1999. View at Google Scholar
  3. J Y Liu, G F Morris, W H Lei, M Corti, and A R Brody, “Up-regulated expression of transforming growth factor-alpha in the bronchiolar-alveolar duct regions of asbestos-exposed rats,” The American Journal of Pathology, vol. 149, no. 1, pp. 205–217, 1996. View at Google Scholar
  4. D E Gómez, D F Alonso, H Yoshiji, and U P Thorgeirsson, “Tissue inhibitors of metalloproteinases: structure, regulation and biological functions,” European Journal of Cell Biology, vol. 74, no. 2, pp. 111–122, 1997. View at Google Scholar
  5. J F Jr Woessner, “The family of matrix metalloproteinases,” Annals of the New York Academy of Sciences, vol. 732, pp. 11–21, 1994. View at Publisher · View at Google Scholar
  6. E Fireman, J Greif, Y Schwarz et al., “Assessment of hazardous dust exposure by BAL and induced sputum,” Chest, vol. 115, no. 6, pp. 1720–1728, 1999. View at Publisher · View at Google Scholar
  7. Y Lerman, B Segal, M Rochvarger, D Weinberg, O Kivity, and E Fireman, “Induced-sputum particle size distribution and pulmonary function in foundry workers,” Archives of Environmental Health, vol. 58, no. 9, pp. 565–571, 2003. View at Google Scholar
  8. E Fireman, Z Kraiem, O Sade, J Greif, and Z Fireman, “Induced sputum-retrieved matrix metalloproteinase 9 and tissue metalloproteinase inhibitor 1 in granulomatous diseases,” Clinical and Experimental Immunology, vol. 130, no. 2, pp. 331–337, 2002. View at Publisher · View at Google Scholar
  9. I Pin, P G Gibson, R Kolendowicz et al., “Use of induced sputum cell counts to investigate airway inflammation in asthma,” Thorax, vol. 47, no. 1, pp. 25–29, 1992. View at Google Scholar
  10. T Popov, R Gottschalk, R Kolendowicz, J Dolovich, P Powers, and F E Hargreave, “The evaluation of a cell dispersion method of sputum examination,” Clinical & Experimental Allergy, vol. 24, no. 8, pp. 778–783, 1994. View at Google Scholar
  11. A Aharonson, N Karasikov, M Krauss et al., “Measurement of particle size in the range of 150–1200µ using the TOT method,” Journal of Aerosol Science, vol. 17, pp. 530–536, 1986. View at Publisher · View at Google Scholar
  12. “Standardization of spirometry—1987 update. Statement of the American Thoracic Society,” The American Review of Respiratory Disease, vol. 136, no. 5, pp. 1285–1298, 1987.
  13. S L Weber and D E Banks, “Silicosis,” in Textbook of Occupational and Environmental Medicine, L Rosenstock and M R Cullen, Eds., pp. 266–267, W.B. Saunders, Philadelphia, Pa, 1994. View at Google Scholar
  14. M Suga, K Iyonaga, T Okamoto et al., “Characteristic elevation of matrix metalloproteinase activity in idiopathic interstitial pneumonias,” American Journal of Respiratory and Critical Care Medicine, vol. 162, no. 5, pp. 1949–1956, 2000. View at Google Scholar
  15. V Ruiz, R M Ordóñez, J Berumen et al., “Unbalanced collagenases/TIMP-1 expression and epithelial apoptosis in experimental lung fibrosis,” American Journal of Physiology. Lung Cellular and Molecular Physiology, vol. 285, no. 5, pp. L1026–L1036, 2003. View at Google Scholar
  16. J Pérez-Ramos, M de Lourdes Segura-Valdez, B Vanda, M Selman, and A Pardo, “Matrix metalloproteinases 2, 9, and 13, and tissue inhibitors of metalloproteinases 1 and 2 in experimental lung silicosis,” American Journal of Respiratory and Critical Care Medicine, vol. 160, no. 4, pp. 1274–1282, 1999. View at Google Scholar
  17. H-S Park, H-A Kim, J-W Jung et al., “Metalloproteinase-9 is increased after toluene diisocyanate exposure in the induced sputum from patients with toluene diisocyanate-induced asthma,” Clinical & Experimental Allergy, vol. 33, no. 1, pp. 113–118, 2003. View at Google Scholar
  18. R EK Russell, S V Culpitt, C DeMatos et al., “Release and activity of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 by alveolar macrophages from patients with chronic obstructive pulmonary disease,” American Journal of Respiratory Cell and Molecular Biology, vol. 26, no. 5, pp. 602–609, 2002. View at Google Scholar
  19. A Churg, “Interactions of exogenous or evoked agents and particles: the role of reactive oxygen species,” Free Radical Biology and Medicine, vol. 34, no. 10, pp. 1230–1235, 2003. View at Publisher · View at Google Scholar
  20. A Churg, M Brauer, M del Carmen Avila-Casado, T I Fortoul, and J L Wright, “Chronic exposure to high levels of particulate air pollution and small airway remodeling,” Environmental Health Perspectives, vol. 111, no. 5, pp. 714–718, 2003. View at Google Scholar