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Mediators of Inflammation
Volume 2006, Article ID 85019, 4 pages
Research Communication

Comparison of Effects of Smoking and Smokeless Tobacco “Maras Powder” Use on Humoral Immune System Parameters

1Department of Microbiology, KSU Medical School, Kahramanmaras 46050, Turkey
2Department of Public Health, KSU Medical School, Kahramanmaras 46050, Turkey
3Department of Family Medicine, KSU Medical School, Kahramanmaras 46050, Turkey

Received 26 November 2005; Revised 8 February 2006; Accepted 14 February 2006

Copyright © 2006 Murat Aral et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. The aim of this study is to assess the impacts of “Maras powder” and cigarette smoking on the parameters of the humoral immune system. Material and Methods. One hundred seventy seven subjects were included in the study. The IgA, IgG, IgM, C3 and C4 levels were detected via nephelometric method. Results. In1.4% of the control group IgM levels were below normal where it was 10.8% and 18.6% in Maras powder group and in cigarette smoking group respectively. The IgM levels of both groups were significantly lower compared to the control group (P<.05). Nonetheless, the IgE levels of Maras powder group and smoking group were found to be remarkably higher compared to the control group (P<.01). Conclusion. Effects of Maras powder on humoral immune response were found to be similar to that of smoking.