Mediators of Inflammation
Volume 2007 (2007), Article ID 23296, 9 pages
http://dx.doi.org/10.1155/2007/23296
Effects of a Combination of Thyme and Oregano Essential Oils on TNBS-Induced Colitis in Mice
Institute of Animal Physiology, Slovak Academy of Sciences, Šoltésovej 4-6, Košice 04001, Slovakia
Received 11 June 2007; Accepted 22 August 2007
Copyright © 2007 Alexandra Bukovská et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
We examined the anti-inflammatory effects of the combination of thyme and oregano essential oil
dietary administered at three concentrations (0.4% thyme and 0.2% oregano
oils; 0.2% thyme and 0.1%
oregano oils; 0.1% thyme and 0.05% oregano oils) on mice with TNBS-induced colitis.
Treatment of colitic
animals with the essential oils decreased the mRNA levels of pro-inflammatory cytokines
IL-1