Association of Single Nucleotide Polymorphisms in the IL-18 Gene with Production of IL-18 Protein by Mononuclear Cells from Healthy Donors

Table 1

Distribution of frequencies of IL-18 gene promoter genotypes at the −607 A→C position in relation to the level of spontaneous IL-18 secretion.

Quantiles of level of spontaneous	IL-18 level	−607CC	−607AN	(pemf)	p𝜒^2
IL-18 secretion	pg/mL	n	n
Low (0–15%)	0–3.4	7	11	0.2031	>0.1
Medium (15–85%)	3.5–95.3	44	57
High (85–100%)	95.4–138	5	19	0.0239	<0.05
All		56	87