Effects of Nebivolol on Endothelial Gene Expression during Oxidative Stress in Human Umbilical Vein Endothelial Cells
Figure 3
Effect of nebivolol and atenolol on RNA expression of endothelin-1 (ET-1), metalloproteinases (MMP-2, MMP-9) and protease inhibitor (TIMP-1) induced by oxidative stress in human umbilical vein endothelial cells (HUVECs). HUVECs were incubated with nebivolol or atenolol (10 μM) for 24 hours at 37°C; oxidative
stress was induced by the addition of oxidized (ox)LDL (50 g protein mL−1).
versus control; † versus ox-LDL. AU = arbitrary units. Data are expressed as of 6 different experiments.
