Research Article

Proinflammation and Hypertension: A Population-Based Study

Table 2

Odds ratios of hypertension (≥140/≥90 mmHg or drug treatment for hypertension) according to quartiles of plasma levels of baseline IL-1β and IL-1ra.

VariableQuartile of plasma levelP for linearity*
IIIIIIIV

IL-1β
Median (range), pg/mL0.25 (0.088–0.378)0.48 (0.379–0.566)0.63 (0.567–0.696)0.82 (0.700–5.540)
Odds ratio (95% CI)1.001.47 (0.79 to 2.73)0.83 (0.43 to 1.58)1.55 (0.84 to 2.89).46

IL-1ra
Median (range), pg/mL84 (46–98)117 (99–139)163 (140–192)244 (193–1134)
Odds ratio (95% CI)1.000.61 (0.31 to 1.20)1.07 (0.56 to 2.04)1.82 (0.95 to 3.46).026

*P-values were calculated by using a logistic model, adjusted for gender, age, follow-up time, and baseline body mass index.